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Mastelli S.r.l.

MASTELLI S.R.L., based in Italy, is a pioneer in regenerative medicine. It is the original developer of PN-HPT® (polynucleotides highly purified technology), featured in products like PLINEST and NEWEST, designed to stimulate dermal repair and skin regeneration at the cellular level.

NEWEST

NEWEST is a CE-marked injectable based on polynucleotides, designed to support skin regeneration and anti-aging. It promotes fibroblast activation, improves dermal density, and restores hydration—making it ideal for delicate areas like the face, neck, and periorbital region.

PLINEST

Plinest® is a leading brand in regenerative aesthetics, developed by Mastelli S.r.l., a pioneer in biotechnological innovation. Known for its patented Polynucleotide-based (PN-HPT®) technology, Plinest offers injectable treatments that stimulate tissue repair, improve skin quality, and restore natural radiance. Clinically proven and CE-certified, Plinest products are ideal for revitalizing the face, eye contour, scalp, and delicate areas, offering personalized anti-aging protocols for medical professionals. Trusted by experts worldwide, Plinest sets the standard for skin bio-revitalization through cellular stimulation, with a product range that includes Plinest, Plinest Eye, Plinest Hair, Plinest Fast and Plinest One.
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